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Spravato® (esketamine)

SPRAVATO® nasal spray is a different kind of medication taken with an oral antidepressant for adults with treatment-resistant depression – a first in decades approved by the FDA.

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If you’ve struggled with depression and tried two or more antidepressants* in your current episode without adequate relief, talk to your provider at Allen Psychiatry to see if you have treatment-resistant depression. This treatment is covered by most insurance. 

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This treatment is for those with depression who have failed at least two antidepressants. Patients will be required to have someone drive them home and will need to stay in our office for two hours. The initial treatment consists of twice weekly treatments for four weeks and then treatment once weekly. Ongoing treatment is usually required.​ 

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Frequently Asked Questions

  • Who is eligible for SPRAVATO® treatment?
    SPRAVATO® treatment is specifically designed for adults who have not responded to at least two different treatments for their current depressive episode, making it a solution for those with treatment-resistant depression. A comprehensive evaluation by a healthcare provider is necessary to determine if SPRAVATO® is an appropriate treatment option for you.
     

  • What can I expect during a SPRAVATO® treatment session?
    During a SPRAVATO® treatment session, you will be in a comfortable setting under supervision. After administering the nasal spray, you will be monitored for at least 2 hours for potential side effects and to ensure your safety. The frequency of treatment sessions typically starts twice a week for the first month, followed by adjustments based on your response to the treatment.
     

  • Are there any side effects of SPRAVATO®?
    Like all medications, SPRAVATO® can cause side effects. Common side effects include dizziness, nausea, sedation, vertigo, decreased feeling or sensitivity (hypoesthesia), anxiety, lethargy, increased blood pressure, vomiting, and feeling drunk. It's important to discuss all potential side effects with your provider before starting treatment.
     

  • How long does it take to see results from SPRAVATO® treatment?
    Response to SPRAVATO® can vary from person to person. Some individuals may notice improvements in their symptoms within the first few weeks of treatment, while others may take longer. Continuous evaluation by your provider is essential to monitor your progress and adjust the treatment plan as needed.
     

  • Will my insurance cover SPRAVATO® treatment?
    Coverage for SPRAVATO® treatment varies by insurance provider and plan. We can assist in navigating insurance coverage.
     

  • Is SPRAVATO® addictive?
    SPRAVATO® contains esketamine, which is a derivative of ketamine, a substance that has the potential for abuse. However, SPRAVATO® is administered under strict medical supervision in a healthcare setting to minimize risks of abuse and dependence. Discuss any concerns about addiction with your provider.
     

  • Can I drive home after my SPRAVATO® treatment?
    Due to potential side effects such as dizziness and sedation, patients are advised not to drive or operate heavy machinery until the next day after a good night's sleep. You will need to arrange for transportation home following your treatment sessions
     

  • How do I get started with SPRAVATO® treatment?
    To begin SPRAVATO® treatment, you'll need a consultation. This is where we evaluate your medical history, current symptoms, and previous treatments to determine if SPRAVATO® is a suitable option for you. If deemed appropriate, we will discuss a treatment plan and next steps.

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